cloning cows

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ruhtram

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I haven't heard of any cloned cows...Good question though, I'd like to hear more!
 

donorheaven

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Cruiser said:
I haven't heard of any cloned cows...Good question though, I'd like to hear more!

Rick Frye cloned his cow and so did Kris Black on Phylli....many others have done it...call Don Coover at Sek Genetics.
 

LostFarmer

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I have heard rumors that the owners of the mother to Whiplash C17 is trying to get her cloned.  Don't know that for sure.
 

kfacres

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here are my thoughts on cloning, as they were origially put on another post.. and copied here.

most of the clones are coming into play, and being gone w/in a year or 2..

The problem with cloning is... especially when you do something old...  Every day, DNA is sluffed off, this is why people need glasses in their old age, and have weak bones, etc.... 

When you clone, you make a copy of the current genetic lineup.. which in the case of something old...  will have all the problems.. So basically, when those cloned calves are born..  You actually have an old grandma cow that is born, into a baby calf.  Or a poor semen producer, who's crippled... into a new AI sire... 

This is why I suspect these clones are coming and leaving so rapidly.. Maybe I'm wrong.. I'm not basing this opinion upon poor semen production,  otherwise every clubby bull out there would be classified "clone". 

If people were smart, and into thinking toward the future.. They would save that cell line as soon as the calf was  born... the good ones get kept and cloned 10 years later.. the bad ones would be discarded.
 

kfacres

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chambero said:
DNA doesnt change with age.

yes it does.. it is lost.. the end of the strands (ladders) is constantly being sluffed off, small peice by small peice.  Go back to school and learn about it.

This is what causes people to need glasses when they get older, lose their hair, get wrinkles, etc...  (the signs of getting old)
 

kfacres

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the truth said:
chambero said:
DNA doesnt change with age.

yes it does.. it is lost.. the end of the strands (ladders) is constantly being sluffed off, small peice by small peice.  Go back to school and learn about it.

This is what causes people to need glasses when they get older, lose their hair, get wrinkles, etc...  (the signs of getting old)

The DNA damage theory of aging proposes that aging is a consequence of unrepaired DNA damage accumulation. Damage in this context includes chemical reactions that mutate DNA and/or interfere with DNA replication. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).[1]

In humans, DNA damage occurs frequently and DNA repair processes have evolved to compensate. On average, approximately 800 DNA lesions occur per hour in each cell, or about 19,200 per cell per day (Vilenchik & Knudson 2000). In any cell some DNA damage may remain despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, which cannot rely on DNA repair mechanisms associated with DNA replication such as those in the brain, skeletal and cardiac muscle.

The first studies on human DNA dosage in regards to age indicated a very substantial loss of DNA from the human tissue as a function of age (Johnson et al., 1975). 
 

bcosu

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not trying to start a fight or stoke any fire but i thought the aging process was when cells died at a faster rate than they were being created/dividing? i understand the idea of dna splitting but as long as the animal is growing it should still be creating cells. i would imagine it would age faster than normal but i can't see it being born with the same faults like crippled joints because that tends to be environmental, too much pressure for too long on poor structure. they would be born straight like heatwave but they wouldn't hunch like him at 10yrs of age.
 

chambero

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That's why they take ear punches to get cell lines from old cattle for cloning - they don't want the offspring to have poor eyesight, chronic hair loss, or crippled due to old DNA in those parts of the body.  They dont care if they are hard hearing.  (really wish I had the little wink icon)

On a more serious note, you have more than a few things confused on the how the aging process, so you might want to retake that class.

You also might want to be sure about the background of someone before throwing darts at them.  Although I'm not a geneticist, i'll lay money I've spent more time in science classes and have more degees and professional licenses related to science on my business card than you.  Lack of time in school isn't my weakness.

DNA doesnt change - at least not significantly enough to matter for this discussion.  Any losses due to age are very random and not uniform from one cell to another.  That's about as much as I care to know.

The people that are cloning know cattle and know the science- when there is a better way to do it, they will.

I would never presume to think I knew more about it than them.
 

kfacres

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chambero said:
That's why they take ear punches to get cell lines from old cattle for cloning - they don't want the offspring to have poor eyesight, chronic hair loss, or crippled due to old DNA in those parts of the body.  They dont care if they are hard hearing.  (really wish I had the little wink icon)

On a more serious note, you have more than a few things confused on the how the aging process, so you might want to retake that class.

You also might want to be sure about the background of someone before throwing darts at them.  Although I'm not a geneticist, i'll lay money I've spent more time in science classes and have more degees and professional licenses related to science on my business card than you.  Lack of time in school isn't my weakness.

DNA doesnt change - at least not significantly enough to matter for this discussion.  Any losses due to age are very random and not uniform from one cell to another.  That's about as much as I care to know.

The people that are cloning know cattle and know the science- when there is a better way to do it, they will.

I would never presume to think I knew more about it than them.

I wish there was a "all hail and bow down icon".  just couldn't resist...  Neg Karma?  please do
 

NSF

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I always thought aging was due to parts just wearing out. Such as in a motor, there isnt a change in the fundamental metallurgy of the parts, they just slowly wear down. Much like peoples knees and joints, people might be genetically predisposed to having those parts wear out sooner than others but it isnt  due to a change in the base DNA. But, I'm not a geneticist. 
 

herfluvr

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Having seen a lot of cloning in the horse world, it is interesting to see the clones go to market.  Not all are valued the same which is surprising since the DNA makeup is the same.  Watched 4 clones sell this last Dec In Ft Worth of Smart Little Lena-one of the most influencial sires in the cow horse industry.  2 sold over 20k and 2 sold less that 6k.  Can't figure that one out.  
Cloning of maternal lines makes a bit more sense as the number of offspring is more limited they say a cloned bull.  One thing that is addressed repeatedly in the horse world is if we continue to clone the stallions and not provide new outcrosses and bloodlines, we will saturate the gene pool and start a wave of genetically inferior offspring.  
I look forward to seeing the crops of new bulls and sires.  If we clone the good ones, we don't have the capacity to move our genetics forward.  
 

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