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Offline nkotb

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One shot Lutalyse
« on: June 14, 2015, 07:32:01 AM »
Had another producer say you are not supposed to breed on the first heat cycle after doing the single shot Lutalyse.  What would be the reasoning?  I'm having trouble seeing how it's ok to breed after lute during the multi-day protocols, but not after the single shot?

Offline O'Brien Show Cattle

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Re: One shot Lutalyse
« Reply #1 on: June 14, 2015, 08:35:54 AM »
She will successfully breed after one shot of Lutalyse if there is a CL present. If not, she will need the second shot 10-12 days after the first.

Offline Lucky_P

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Re: One shot Lutalyse
« Reply #2 on: June 14, 2015, 10:16:16 AM »
There is no reasoning; they're just parrotting misinformation they heard from someone else.
As O'BSC said, prostaglandin injection will only 'bring them into heat', if they have a CL on the ovary following a previous ovulation.   Estrus following injectible prostaglandin-induced lysis of that CL should be just as fertile as one resulting from normal cyclical lysis of the CL, or, for that matter, one resulting from a second injection 11 days later.

Back in the day, before CIDRs, etc. - and I still do it sometimes - we'd watch for heat for 5 days, breed any that came in in that time frame, then give a prostaglandin injection to any that hadn't shown heat in those 5 days... and anticipate that the vast majority will be in heat in the next 36-72 hrs.

Offline nkotb

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Re: One shot Lutalyse
« Reply #3 on: June 14, 2015, 04:28:07 PM »
That was my inclination, but it did get me wondering.

Offline stevegarza

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Re: One shot Lutalyse
« Reply #4 on: June 14, 2015, 07:12:41 PM »
(Please correct me if I'm wrong) Along time ago I used to A.I. for large producer and he didn't feel comfortable breeding cows very soon after a lutalyse injection.  His theory was that it would kill the ovum (egg).  Kind of how lutalyse would cause an abortion in early pregnancies.  Of course he didn't mind having a cow bred if she came into heat a few days after the injection.

Offline Lucky_P

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Re: One shot Lutalyse
« Reply #5 on: June 14, 2015, 08:41:54 PM »
 sg,
I'm not a reproductive physiologist, and don't play one on TV (but I am a veterinarian) - but a lot of folks have no clue about even the most basic info - or they've received misinformation from someone - or misinterpreted what they were told.  Sometimes it's hard to get past old spouses' tails and deeply ingrained misconceptions.

The prostaglandins(Lutalyse, Estrumate, etc.) don't really have any direct effect on the ovum; they cause lysis/regression of the corpus luteum, allowing the next ovum 'in line' to mature and ovulate. 
Abortion early in pregnancy due to prostaglandin injection is because the CL (which produces progesterone, to maintain the pregnancy) is lysed... the conceptus is aborted, and a new wave of follicular development occurs.

 

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