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Offline -XBAR-

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Re: Myostatin gene
« Reply #105 on: August 09, 2019, 10:01:12 AM »
https://link.springer.com/content/pdf/10.1186/1297-9686-35-1-103.pdf

Given the minimal frequency in which its expressed,  do you feel the cost, time, and labor being spent on this topic is warranted ?

Offline knabe

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Re: Myostatin gene
« Reply #106 on: August 09, 2019, 10:26:17 AM »
Depends if it was an animal I wanted a lot of offspring out of.

The other way to look at it is 28 people die in hospitals every day from misdiagnosis, mistakes etc but no one is screaming for to ban hospitals

I dont understand the lack of outrage.

So in short, it depends.

I guess at some level one could say the same thing about every post on steer planet.
"The generation that told us to question authority, has now become the Authority we cannot question!"

Offline Okotoks

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Re: Myostatin gene
« Reply #107 on: August 09, 2019, 12:21:52 PM »
I guess it depends on one's tolerance for dystocia. Our neighbor had a wreck with it last year with $1500 worth of vet bills and two dead calves. His current bull is myostatin free. Is this topic relevant to him?
I used two heifer bulls one was a 84 lb BW and one was 72 lb. As long as they were mated to none carriers life was good but I had c sections out of both of them from from carrier heifers that had affected calves. I sell bulls into the commercial market, if they are tested free I know my bull customers cannot have affected calves so it it is relevant to me.
I AI'd a couple of free cows to a carrier bull this year, I will test the calves. I have some carrier cows, I test their calves, knowledge of their status allows me to make breeding decisions.

Offline Dale

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Re: Myostatin gene
« Reply #108 on: August 09, 2019, 01:04:47 PM »
https://csa.digitalbeef.com/modules.php?op=modload&name=_miscellaneous&file=genetic_conditions

More myostatin will be found as U.S. breeders increasingly test for DM.  Surely Canadians do not like to waste money, and they test as a service to their customers.  It is a North American problem, and there are already dozens of E226X carriers found in Canada, including some with genetics from south of the border. 

Offline aj

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Re: Myostatin gene
« Reply #109 on: August 09, 2019, 05:33:06 PM »
Thanks Dale......worth clicking on.
People can't believe we have such a big moon for such a small town.

Offline knabe

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Re: Myostatin gene
« Reply #110 on: August 09, 2019, 11:01:06 PM »
improver 3rd and jpj . interesting

"The generation that told us to question authority, has now become the Authority we cannot question!"

Offline -XBAR-

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Re: Myostatin gene
« Reply #111 on: August 09, 2019, 11:18:21 PM »
I guess it depends on one's tolerance for dystocia. Our neighbor had a wreck with it last year with $1500 worth of vet bills and two dead calves. His current bull is myostatin free. Is this topic relevant to him?
I used two heifer bulls one was a 84 lb BW and one was 72 lb. As long as they were mated to none carriers life was good but I had c sections out of both of them from from carrier heifers that had affected calves. I sell bulls into the commercial market, if they are tested free I know my bull customers cannot have affected calves so it it is relevant to me.
I AI'd a couple of free cows to a carrier bull this year, I will test the calves. I have some carrier cows, I test their calves, knowledge of their status allows me to make breeding decisions.

Im confused as to why your experiences are so different from those of Saskvalley and Muridale, both of whom have posted that out of several hundred calves theyve had two homozygotes? 

Offline mark tenenbaum

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Re: Myostatin gene
« Reply #112 on: August 09, 2019, 11:34:18 PM »
I guess it depends on one's tolerance for dystocia. Our neighbor had a wreck with it last year with $1500 worth of vet bills and two dead calves. His current bull is myostatin free. Is this topic relevant to him?
I used two heifer bulls one was a 84 lb BW and one was 72 lb. As long as they were mated to none carriers life was good but I had c sections out of both of them from from carrier heifers that had affected calves. I sell bulls into the commercial market, if they are tested free I know my bull customers cannot have affected calves so it it is relevant to me.
I AI'd a couple of free cows to a carrier bull this year, I will test the calves. I have some carrier cows, I test their calves, knowledge of their status allows me to make breeding decisions.
/// JMO You are right on target-Its NOT as much about hiding your head in the sand and eliminating really good cattle you may have worked many years to achieve as to keeping things manageable-Just like the other defects-Breed a dirty one clean and dont lose the phenotype it took so long to produce etc-Just dont breed a carrier to the wrong carrier-and if you have enough of them the numbers will work in your favor- Clean ones will appear where they otherwise would not have had a chance O0

Offline Okotoks

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Re: Myostatin gene
« Reply #113 on: August 10, 2019, 12:27:57 AM »
I guess it depends on one's tolerance for dystocia. Our neighbor had a wreck with it last year with $1500 worth of vet bills and two dead calves. His current bull is myostatin free. Is this topic relevant to him?
I used two heifer bulls one was a 84 lb BW and one was 72 lb. As long as they were mated to none carriers life was good but I had c sections out of both of them from from carrier heifers that had affected calves. I sell bulls into the commercial market, if they are tested free I know my bull customers cannot have affected calves so it it is relevant to me.
I AI'd a couple of free cows to a carrier bull this year, I will test the calves. I have some carrier cows, I test their calves, knowledge of their status allows me to make breeding decisions.

Im confused as to why your experiences are so different from those of Saskvalley and Muridale, both of whom have posted that out of several hundred calves theyve had two homozygotes?
I think it's because I introduced the myostatin to my herd a dozen years earlier and then brought it back in. The fact the test became available will probably prevent a lot of doubling up and a lot of grief. A breeder can use a myostatin carrier now and follow with a clean bull and not run into any trouble if he keeps track
« Last Edit: August 10, 2019, 12:29:00 AM by Okotoks »

Offline aj

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Re: Myostatin gene
« Reply #114 on: August 10, 2019, 09:12:14 AM »
Are you sure you are on the right column Knabe. Somehow I got the DS column first.
People can't believe we have such a big moon for such a small town.

Offline knabe

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Re: Myostatin gene
« Reply #115 on: August 10, 2019, 11:23:54 AM »
Says carrier on both.


And double stuff too, so now hes quadruple stuff.


And improver himself.


I always wondered if some of these alleles in homo state added any thickness.


No way to know without crisper probably.
« Last Edit: August 10, 2019, 11:27:39 AM by knabe »
"The generation that told us to question authority, has now become the Authority we cannot question!"

Offline aj

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Re: Myostatin gene
« Reply #116 on: August 10, 2019, 01:39:46 PM »
I couldn't find that JPJ was a 226 carrier.
People can't believe we have such a big moon for such a small town.

Offline Dale

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Re: Myostatin gene
« Reply #117 on: August 21, 2019, 01:14:50 PM »
Homeplace Hot Commodity 1625 is myostatin free of all three mutations.  The test results came back today.  It is on digitalbeef, if you want to look it up.

Offline Okotoks

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Re: Myostatin gene
« Reply #118 on: December 21, 2019, 11:44:37 AM »
Attached are the DNA results for Mandalong Super Flag showing him free of myostatin variants. Another animal to remove from the speculation list!

Offline aj

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Re: Myostatin gene
« Reply #119 on: December 22, 2019, 07:27:00 PM »
Interesting. Thanks
People can't believe we have such a big moon for such a small town.

 

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