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Offline mark tenenbaum

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Re: Myostatin gene
« Reply #165 on: July 21, 2020, 07:34:27 PM »
I don't understand knabe's post and his list of bulls. Double Stuff isn't positive for myostatin is he?///// LOL O0 <alien>

Offline knabe

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Re: Myostatin gene
« Reply #166 on: July 21, 2020, 09:20:53 PM »
Do bulls that carry the Myostatin gene tend to have smaller testicles?

Not sure about that. But if they are homozygous , then yes, definitely.
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Offline knabe

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Re: Myostatin gene
« Reply #167 on: July 21, 2020, 09:25:13 PM »
I don't understand knabe's post and his list of bulls. Double Stuff isn't positive for myostatin is he?///// LOL O0 <alien>

Makes sense. Brings to mind a whole new set of bulls

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Offline Hopster1000

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Re: Myostatin gene
« Reply #168 on: July 22, 2020, 02:25:10 AM »
From my own personal experience the affects of the myostatin deletion are not at all consistent. I have a double muscled SH cow. Fairly sure she has 2 copies. She is very muscled, but has calved unassisted, has enough milk and is a good mother. Calves are about 38kg (which is small for here) they don't show muscle at the start, but then do after a couple of weeks.
As with most herds there are a few carriers. One or two carriers seem a bit harder to calf, but most don't. Myostatin free cows that then have myostatin carrier calves are also inconsistent as some calves are larger while many are normal at birth and develop some muscle later. The muscle development is also inconsistent as some carrier calves can have defined muscle while some are the softest easiest fleshing.
Bull testicle size is not consistent either as I had a carrier bull with very large testicles. Some are obviously smaller but I haven't seen a carrier bull with testicles that are too small.  Homogeneous SH bulls can't be registered here so not sure about their testicle size.
All these example would be for the same myostatin deletion.

Offline aj

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Re: Myostatin gene
« Reply #169 on: September 06, 2020, 05:49:52 PM »
El bumpo.
People can't believe we have such a big moon for such a small town.

Offline knabe

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Re: Myostatin gene
« Reply #170 on: September 06, 2020, 07:28:24 PM »
Please provide info instead of just bumping thread.

Thunderhead is dm free.  Not that he was a suspect.

https://maine-anjou.digitalbeef.com/modules.php?op=modload&name=_animal&file=_animal&animal_registration=58

Click on dna tab.
« Last Edit: September 06, 2020, 07:37:08 PM by knabe »
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Offline librarian

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Re: Myostatin gene
« Reply #171 on: February 01, 2021, 03:43:53 PM »
I have not read this entire thread, so forgive me if this has been mentioned before. Check out the genetic conditions page on the Canadian Association site, especially the E226x results. I really commend the Associations for making this information visible and the breeders for testing. https://csa.digitalbeef.com/modules.php?op=modload&name=_miscellaneous&file=genetic_conditions
'Those who do not understand the old will not understand the new'. -farmers quote

Offline knabe

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Re: Myostatin gene
« Reply #172 on: February 02, 2021, 11:10:12 AM »
What is the end game of the double muscle mutants.

Piedmontese type product?

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Offline librarian

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Re: Myostatin gene
« Reply #173 on: February 02, 2021, 01:21:34 PM »
What is the end game of the double muscle mutants.

Piedmontese type product?
If one could consider the kind of study I do education, then an educated guess would be that the end game of these mutations is a metabolic, adrenal and melanistic adjustment to the rigors of life as a tool of medieval peasants.
From A List of Foods of Medieval Times: The majority of peasants worked as farmers, growing foodstuffs and rearing cattle for their landlords, who were often rich or part of the nobility. While meat was destined for the landlords, milk and eggs were generally more accessible to the peasants. Adults rarely consumed milk, and cheese was the main source of protein for the poor, together with beans and peas. The upper classes also ate cheese, but preferred types that were very salty and aged.
How such energetic adjustments become fixed is beyond my ability to form an opinion on, I doubt if such processes are well understood by even the most daring evo-devonauts. Im venturing there is crosstalk, before cell type differentiation and in waves during embryogenesis, between the hormones that originate in the pituitary gland. Interrupting the synthesis of one hormone has effects upon others, expressed in continuous fashion according to environmental stress.
I would say artisanal cheese is the end game, since artillery hauling oxen are obsolete.  Optimal Beef production with these mutations seems fraught with pre and post slaughter considerations that require casually shooting an aged animal as it peacefully ruminates and slowly cooling the meat.

https://www.healthline.com/health/human-body-maps/pituitary-gland#anatomy-and-function

The anterior lobe of your pituitary gland is made up of several different types of cells that produce and release different types of hormones, including:

Growth hormone. Growth hormone regulates growth and physical development. It can stimulate growth in almost all of your tissues. Its primary targets are bones and muscles.
Thyroid-stimulating hormone. This hormone activates your thyroid to release thyroid hormones. Your thyroid gland and the hormones it produces are crucial for metabolism.
Adrenocorticotropic hormone. This hormone stimulates your adrenal glands to produce cortisol and other hormones.
Follicle-stimulating hormone. Follicle-stimulating hormone is involved with estrogen secretion and the growth of egg cells in women. Its also important for sperm cell production in men.
Luteinizing hormone. Luteinizing hormone is involved in the production of estrogen in women and testosterone in men.
Prolactin. Prolactin helps women who are breastfeeding produce milk.
Endorphins. Endorphins have pain-relieving properties and are thought to be connected to the pleasure centers of the brain.
Enkephalins. Enkephalins are closely related to endorphins and have similar pain-relieving effects.
Beta-melanocyte-stimulating hormone. This hormone helps to stimulate increased pigmentation of your skin in response to exposure to ultraviolet radiation.
'Those who do not understand the old will not understand the new'. -farmers quote

Offline Dale

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Re: Myostatin gene
« Reply #174 on: February 02, 2021, 03:25:37 PM »
"I have not read this entire thread, so forgive me if this has been mentioned before. Check out the genetic conditions page on the Canadian Association site, especially the E226x results. I really commend the Associations for making this information visible and the breeders for testing. https://csa.digitalbeef.com/modules.php?op=modload&name=_miscellaneous&file=genetic_conditions"

I second that.  Canada's version of digitalbeef has a ton of useful info.  If you look up Muridale Robert on the Canadian site, he has 57 progeny and Robert is free of all 3 myostatin conditions.  Canadians need to be commended for their leadership and transparency in myostatin testing!

 

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