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  1. HerefordGuy

    Obese gene

    Animals were not pooled, each animal was individually genotyped.
  2. HerefordGuy

    Obese gene

    Here is the research paper. http://www.biomedcentral.com/1471-2164/13/606 Plots are in the supplementary material. We collected as many Angus AI sires as we could get our hands on. Most of these represent Angus sires with large numbers of progeny, but also includes unique populations like the...
  3. HerefordGuy

    Obese gene

    How much of the phenotypic or genetic variance is this leptin test accounting for? If this leptin variant was a causal mutation of large (or moderate) effect, the p-values would be very small and highly significant. It would also be replicated across independent experiments. In 2006, Taylor's...
  4. HerefordGuy

    Obese gene

    When we do genome-wide analysis for marbling in Angus, we don't see any large effects, all we see is thousands of small effects. I disagree that there is low-hanging fruit, especially for marbling.
  5. HerefordGuy

    Obese gene

    knabe is not talking about introgressing technology, he is  interested in introgressing genes like they do in plant genetics.
  6. HerefordGuy

    Obese gene

    You have the right to your opinion, but your opinion is not backed up by evidence. The rate of genetic progress has increased dramatically (I  can't share the specific amount because Curt Van Tassell has not yet published his research) in dairy cattle since they started using genomic...
  7. HerefordGuy

    Obese gene

    knabe- You want to introgress marbling alleles from Angus? Cross your Maines with top Angus sires, make F2s, test with the GeneMax test and keep the animals that score higher on the marbling score. This should select animals that have the Angus haplotype. You might want to also select for Maine...
  8. HerefordGuy

    Obese gene

    I find it ridiculous that in 2014 people are still trying to use single gene tests to predict performance of traits that are controlled by hundreds of genes. The reported p-values are not impressive and would not be noteworthy in a genome-wide analysis. You would be much better served by...
  9. HerefordGuy

    Blog: A Steak in Genomics

    A Steak in Genomics: Use Genomics to Maximize Dairy-Beef Crossbreeding http://steakgenomics.blogspot.com/2014/04/use-genomics-to-maximize-dairy-beef.html Wulf's and others are developing interesting programs to better utilize dairy cows to produce beef.
  10. HerefordGuy

    Heifer Synchronization Protocols

    I believe the repro folks at Mizzou have had good success with the 14-Day CIDR protocol. http://www.iowabeefcenter.org/estrussynch/s32.pdf
  11. HerefordGuy

    Blog: A Steak in Genomics

    Knabe- I thought I answered this post, but now I don't see it. Must have closed the browser before hitting Post. Let's try again. Not sure I understand this question. Are you asking about the difference between EPDs calculated on a single herd versus EPDs calculated nationally? I personally...
  12. HerefordGuy

    Blog: A Steak in Genomics

    Adapting Breeding Practices to Genomic Technologies http://steakgenomics.blogspot.com/2014/03/adapting-breeding-practices-to-genomic.html This new technology opens new doors. But, it will also require that we adapt some of our current breeding and testing practices.
  13. HerefordGuy

    Blog: A Steak in Genomics

    Another great video about how Angus producers use genomic-enhanced EPDs. I comment on my blog, http://steakgenomics.blogspot.com/2014/02/yon-family-farms-use-genomic-test-to.html, highlighting other approaches to using genomic-enhanced EPDs.
  14. HerefordGuy

    Blog: A Steak in Genomics

    Steak in Genomics: New Prices for Limousin Genetic Tests Announced http://steakgenomics.blogspot.com/2014/02/new-prices-for-limousin-genetic-tests.html
  15. HerefordGuy

    Blog: A Steak in Genomics

    Steak in Genomics: Crossbred Replacement Females Average $529 More Than Straightbred http://steakgenomics.blogspot.com/2014/02/crossbred-replacement-females-average.html
  16. HerefordGuy

    Genetic Defects

    Here are some links to my thoughts. http://beefmagazine.com/cattle-genetics/truth-every-living-thing-genetic-defect-carrier http://connect.ksre.ksu.edu/p1s5q9x50x5/?launcher=false&fcsContent=true&pbMode=normal http://steakgenomics.blogspot.com/2013/08/cattlemen-can-avoid-passing-on-broken.html...
  17. HerefordGuy

    Blog: A Steak in Genomics

    A Steak in Genomics "Fawn Calf" Genetic Test Being Redesigned To Be More Accurate in Gelbvieh Pedigrees http://steakgenomics.blogspot.com/2014/01/fawn-calf-genetic-test-being-redesigned.html
  18. HerefordGuy

    Blog: A Steak in Genomics

    I left a comment on my blog: http://steakgenomics.blogspot.com/2013/12/angus-association-announces-third.html?showComment=1386646190499#c8272901803002201945. A more technical explanation. When new haplotypes are sampled from the population the genomic predictions become more robust. Animals...
  19. HerefordGuy

    Blog: A Steak in Genomics

    Thanks for catching that! It is fixed now.
  20. HerefordGuy

    Blog: A Steak in Genomics

    A Steak in Genomics Angus Association Announces Third Recalibration of Zoetis HD 50K Prediction http://steakgenomics.blogspot.com/2013/12/angus-association-announces-third.html I would be happy to answer any questions readers may have about recalibration.
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