epigenetics

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knabe

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in case you thought genes was everything.

saw this link on another site.

http://www.pbs.org/wgbh/nova/genes/

pay special attention to methylation.  this pattern may be heritable and may not be modulated at the chromsome level.  hm, so an ingredient in plastics are causing us to be obese.  high soy is also interesting, as a "blocker" but also has an effect on testosterone that is not well understood, but is used to modulate testosterone in prisons in china.
 

knabe

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here's a followup link on this popular thread

http://www.sciencemag.org/cgi/content/full/294/5549/2113
 

knabe

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more useless reading, but shorter

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WDG-458PBP2-7N&_user=145269&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000012078&_version=1&_urlVersion=0&_userid=145269&md5=be247e75f6a2a9cec6fb78b9637dbd89

this could be a big difference between an animal from a clone which uses a different cell than a flush mate, or perhaps even flushing interrupts this cascade and perfect restarting does not occur after thawing from freezing meaning it's better to use synchrinization as oppossed to purchasing frozen embryo's, ie purchase flushes and get them in cows rather than archiving the embryo's.  those natural service calves may have an advantage.  throw in unknown environmental factors that may affect methylation and get better calves the natural way.  ugh.
 
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