knabe
Well-known member
just read an interesting article in "thescientist" titled mendel upended.
very interesting. what is proposed is a storage mechanism for revertants to wild type that may be rna in nature as a template to use to revert and incorporate back into the genome. other mechanisms are very large insertions, up to 5700 base pairs, as a result of environmental conditions, and is heritable. this would be another mechanism other than methylation that would store environmental information and allow an organism to accumulate adapatation. this may explain why it may take a generation or two for outcrosses, though outstanding to show an effect and why some people may experience average results from supposedly superior individuals. a superior individual who had accumulated environmental factors in their genome, could actually perform far worse when moved to a different environment. this may explain why individuals which contain both TH and PHA are so unique. it would be interesting to determine if these mutations are inducible, not that we would want to do that, but that if it was possible, one could easily think of a production system to impose as being just as if not more important than genetics and epd's from different environments.
obviously one would have trouble reverting being homozygous recessive lethal. i wonder though if the ratio of mating carriers to carriers might have a population that violated 1:2:1 and had revertancy. i know, it's a stretch, since the calf can obviously grow a lot, while in plants, if it's lethal beyond the one cell stage, that's a different selection criteria. I wonder if herda in quarter horses is the same.
still would like to see the sequence of the PHA gene lined up with say 50 each offsrping from irish whiskey, paramount, dalton, stinger, draft pick, ice pick, 4072 cow, XL 26K ET, etc, who by the way finally showed up as PHAC in this month's list in the voice. i have a direct daughter from this cow, and she is PHAF, and her daughter from a confirmed carrier bull is also free, which, i know, i've repeatedly stated ad nauseum.
also in the voice, in the article about carcass "progress" it was mentioned there were 3 markers for QG. There are 4.
very interesting. what is proposed is a storage mechanism for revertants to wild type that may be rna in nature as a template to use to revert and incorporate back into the genome. other mechanisms are very large insertions, up to 5700 base pairs, as a result of environmental conditions, and is heritable. this would be another mechanism other than methylation that would store environmental information and allow an organism to accumulate adapatation. this may explain why it may take a generation or two for outcrosses, though outstanding to show an effect and why some people may experience average results from supposedly superior individuals. a superior individual who had accumulated environmental factors in their genome, could actually perform far worse when moved to a different environment. this may explain why individuals which contain both TH and PHA are so unique. it would be interesting to determine if these mutations are inducible, not that we would want to do that, but that if it was possible, one could easily think of a production system to impose as being just as if not more important than genetics and epd's from different environments.
obviously one would have trouble reverting being homozygous recessive lethal. i wonder though if the ratio of mating carriers to carriers might have a population that violated 1:2:1 and had revertancy. i know, it's a stretch, since the calf can obviously grow a lot, while in plants, if it's lethal beyond the one cell stage, that's a different selection criteria. I wonder if herda in quarter horses is the same.
still would like to see the sequence of the PHA gene lined up with say 50 each offsrping from irish whiskey, paramount, dalton, stinger, draft pick, ice pick, 4072 cow, XL 26K ET, etc, who by the way finally showed up as PHAC in this month's list in the voice. i have a direct daughter from this cow, and she is PHAF, and her daughter from a confirmed carrier bull is also free, which, i know, i've repeatedly stated ad nauseum.
also in the voice, in the article about carcass "progress" it was mentioned there were 3 markers for QG. There are 4.