knabe
Well-known member
dna is not static.
it does change, for some problems, it only takes one basepair, ie pha or th and countless other defects, obviously many more are more mysterious.
an interesting experiment would be to grab the 10 eggs of a cow at say one year, sequence them in a haploid state, then say 10 years later, sequence to more and compare.
telomeres, the ends of chromosomes erode over time. errors occur as well otherwise there wouldn't be a need for error correction.
perhaps some of the confusion of change is crossover events during meiosis generating change.
spontaneous events occur as well like PHA. also, duplications occur as do deletions during replication and if in the germ line or donor line, things will change. granted, these occur during meiosis. also, it's widely known that all kinds of mutations occur from external events such as radiation, cancer,gamma rays who knows what else. one only needs a reference and a time line to track them over time.
since sequencing is so cheap now, it would be useful to sequence both heat wave and say 10 clones.
if dna didn't change, we wouldn't have speciation.
one or two clones of smart little lena had monkey mouth. would be useful to figure that out.
it does change, for some problems, it only takes one basepair, ie pha or th and countless other defects, obviously many more are more mysterious.
an interesting experiment would be to grab the 10 eggs of a cow at say one year, sequence them in a haploid state, then say 10 years later, sequence to more and compare.
telomeres, the ends of chromosomes erode over time. errors occur as well otherwise there wouldn't be a need for error correction.
perhaps some of the confusion of change is crossover events during meiosis generating change.
spontaneous events occur as well like PHA. also, duplications occur as do deletions during replication and if in the germ line or donor line, things will change. granted, these occur during meiosis. also, it's widely known that all kinds of mutations occur from external events such as radiation, cancer,gamma rays who knows what else. one only needs a reference and a time line to track them over time.
since sequencing is so cheap now, it would be useful to sequence both heat wave and say 10 clones.
if dna didn't change, we wouldn't have speciation.
one or two clones of smart little lena had monkey mouth. would be useful to figure that out.