Post leg syndrome

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kfacres

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I was going to suggest finding an old semen catalog, from 8-10 years ago.. and looking in the section of 'clubby, 3 way x, or composite bulls'  that'd be about all you need to know...

seriously, I'd do a search live fff said above.. google is an amazing tool
 

Show Heifer

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Might also look under spastic psesis (sorry for bad spelling)  This is a genetic disorder prevalent in todays "clubbie", and maine world.
You wont' find it in any semen catalogs, as it is one of those "nasty little secrets"....

There has been several discussions on SP about spastic psresis (again, sorry on the spelling). Do a search, you'll find more than you want!!
 

knabe

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Shady Lane said:
Has this defect been genotyped yet?

Is their a DNA test available?

cunia is a suspect.  he also definitely carries monkey mouth.

i think the Maine association paid Dr. Beever to develop a test for it.  too many bulls are probably carriers.

what would really be a bummer is if Black Gold was a carrier.  he probably is.  no one has ever said he (black gold) had a monkey mouth or a spastic paresis calf.  if cunia is a carrier for both, it's almost impossible black gold doesn't have one or both.  black gold shows up in a good portion of black maine pedigrees.

http://abri.une.edu.au/online/cgi-bin/i4.dll?1=20352036&2=2420&3=56&5=2B3C2B3C3A&6=59245C5B2621582320

 

DL

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believe knabe has lost his mind - the AMAA did not pay Dr B  - nor would he accept $ from an association -

spastic paresis (Elso heel) is a neurological disorder of the hindlimbs of unknown inheritance that affects all breeds of cattle - search on this site for more info

there is not a DNA test - it is not clear if the mutation that causes SP in one breed is the same as the mutation that causes SP in another breed - it is difficult to develop a DNA test if people don't send in samples and pedigree from affected calves
 

Show Heifer

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DL said:
believe knabe has lost his mind - the AMAA did not pay Dr B  - nor would he accept $ from an association -

spastic paresis (Elso heel) is a neurological disorder of the hindlimbs of unknown inheritance that affects all breeds of cattle - search on this site for more info

there is not a DNA test - it is not clear if the mutation that causes SP in one breed is the same as the mutation that causes SP in another breed - it is difficult to develop a DNA test if people don't send in samples and pedigree from affected calves

Those darn Ostriches... it is indeed hard to get a dna test when it NEVER happens to certain bulls.
 

grpeart

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Thanks for the help ,Elso heel will tell you what it is, and is easly understood by anyone. It is found in the google search.
 

knabe

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DL said:
believe knabe has lost his mind - the AMAA did not pay Dr B  - nor would he accept $ from an association -

here's a quote from last november's voice.  from meeting minutes in nov
"Chairman Nessler reported that when we are ready, Dr Beever is ready to start work on a DNA marker test for Spastic Paresis. Consensus was to wait until the last wrinkles are worked out of the reporting issues for PHA."

i assume this might mean some sort of cooperation with either samples, money or both?

don't know what "when we are ready" means.  not sure accepting money from an association or any entity such as the michael j. fox whatever matters.  when i was at stanford, we took money from them, and other "funding" institutions.  there is no higher status in not taking money to cover costs.  taking it from the taxpayer might be on the same plane as taking money from an association.  he gets his money from somewhere.  what's so terrible about an association? 
 

DL

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knabe - glad you found your mind! I believe that science should not be tainted by the money and therefore control from an association - it is a bit like the fox guarding the hen house - Dr B does not get his money for breed associations - you can see how well that type of arrangement worked by looking at the long nosed dwarf.... :eek:
 

simtal

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knabe said:
don't know what "when we are ready" means.  not sure accepting money from an association or any entity such as the michael j. fox whatever matters.  when i was at stanford, we took money from them, and other "funding" institutions.  there is no higher status in not taking money to cover costs.  taking it from the taxpayer might be on the same plane as taking money from an association.  he gets his money from somewhere.  what's so terrible about an association? 

if your at a university, you are a research prostitute. You have to be, it's the only thing that matters.  bottomline, if your group isn't pulling in the dollars (which means earmark for the university) then you better be good at something else.  The association is doing him a favor.

 

DL

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it is no favor when the association controls the use of the test in exchange for the $ - Dr B does not get his money for breed associations - you can see how well that type of arrangement worked by looking at the long nosed dwarf....
 

knabe

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DL said:
it is no favor when the association controls the use of the test in exchange for the $ - Dr B does not get his money for breed associations - you can see how well that type of arrangement worked by looking at the long nosed dwarf....

that was a mistake in negotiations, not due to where the money came from.  the long nose dwarf project could have been rejected or negotiated.

agree it is no favor when the association controls the use of the test just as it is no favor to producers who could do the test themselves if they knew the sequence.  a lot more research could be furthered if the gene was known and if more researchers knew what the linkage group was.  more people could do some interesting linkage group research.  cross species studies could be done to determine lots of things.  one could put all the tests on the 500,000K chip and reduce the cost significantly on a per feature basis.  chips aren't perfect though, but you could easily build some redundancy in.

what's good for the goose is good for the gander.

Dr. Beever rightly decided to license the tests as it wasn't useful for him to be the only one's doing the test.  he's a researcher, not a production unit, and by his own admission, not highly automated.  granted, the companies had some growing pains ramping up and the quality control wasn't quite good.  but no one is perfect.
 

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